Radiptherapy Breast-conserving Therapy
TARGIT Therapy for Breast Cancer
TARGIT Definitive Treatment
TARGIT Definitive Treatment
The TARGIT Trial
The TARGIT trial is an international randomized clinical trial designed to test the hypothesis that the strategy of delivering a single dose of targeted intraoperative radiotherapy in women with early breast cancer is equivalent to a conventional course of post-operative external beam radiotherapy (EBRT). The primary endpoints are local and loco-regional recurrence rates.


Breast-Conserving Radiotherapy, when conventional external beam radiation therapy (EBRT) is not an option
In patients presenting with a local recurrence after previous radiotherapy, repeated external irradiation is no longer indicated in many cases, leaving radical mastectomy as the only treatment alternative. Radiotherapy with INTRABEAM can provide a treatment option for patients after external irradiation is no longer indicated, offering an important alternative improving quality of life and treatment outcomes.

Kraus-Tiefenbacher et al.: Intraoperative radiotherapy (IORT) is an option for patients with localized breast recurrences after previous external-beam radiotherapy. BMC Cancer 2007; 7:178.

Keshtgar et al.: Use of intra-operative radiotherapy [IORT] alone in breast cancer patients when conventional external beam radiation therapy [EBRT] was not possible. Proceedings ESSO, 2006

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More information on the TARGIT trial